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Notre Dame vs. USC picks, predictions, odds: Who wins college football game?

Jeremy Cluff
Arizona Republic
Will Notre Dame upset USC in Saturday's college football game in Los Angeles?

The Notre Dame Fighting Irish and the USC Trojans face off in a Week 13 college football game on Saturday in Los Angeles.

Which team will win the college football game?

Check out these picks, predictions and odds for the game, which is scheduled to begin at 5:30 p.m. MST and can be seen on ABC.

USC is a 5-point favorite in the game, according to Tipico Sportsbook.

The over/under for the game is set at 64.5 points.

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Fan Duel: USC 35, Notre Dame 31

Larry Rupp writes: "The Trojans are 6-0 straight up in their last six home games and I trust them to get the job done here."

OddsChecker: Take Notre Dame with the points vs. USC

Jason Radowitz writes: "Although this game is in Los Angeles, Notre Dame's defense is more likely to earn more stops in this game. Back the Fighting Irish against the spread in a potential stunner."

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Doc's Sports: Go with USC to cover vs. Notre Dame

Josh Schonwald writes: "Over the course of the season so far, the Trojans have earned 3,639 passing yards along with holding an average of 330.8 passing yards per game, putting them at 4th in the country. When it comes to how much they score, the Trojans rank 3rd in D-1 with an average of 42.9 points per outing."

Sports Chat Place: Take Notre Dame with the points against USC

It writes: "I’m going to take a stab on the Irish. Notre Dame put on a defensive clinic versus Boston College in their last game, holding the Eagles to 173 total yards, 11 first downs and five turnovers. Matching up with USC is obviously going to be a much tougher test, however the Irish are on a nice run with 35 or more points in each of their last five games."

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Picks and Parlays: Notre Dame 34, USC 30

It writes: "We think the Irish pull of the upset this weekend in Memorial Coliseum.  The Irish have been on a roll in recent history and are 5-0 in their last 5 games. We think this will be an exciting game from start to finish. Our best bet is ND +5.5."

ESPN: USC has a 65.5% chance to win

The site gives Notre Dame a 34.5% shot to pick up the victory.

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