NFL Week 10 picks, predictions for Vikings vs. Bills, Chargers vs. 49ers, other games

The NFL Week 10 schedule has some interesting games.
Which teams will get victories in those games?
Check out The Arizona Republic's picks and predictions for each game on the Week 10 NFL schedule.
Click on each game for picks and predictions for that game from other sites. All times MST.
- Falcons vs. Panthers | Seahawks vs. Bucs | Vikings vs. Bills
- Lions vs. Bears | Jaguars vs. Chiefs | Browns vs. Dolphins
- Texans vs. Giants | Saints vs. Steelers | Broncos vs. Titans
- Colts vs. Raiders | Cowboys vs. Packers | Cardinals vs. Rams
- Chargers vs. 49ers | Commanders vs. Eagles | Point spreads
Thursday Night Football schedule
Atlanta Falcons vs. Carolina Panthers, 6:15 p.m., Amazon Prime Video
These two teams played a thriller in Week 8, with the Falcons winning 37-34 in overtime. It won't be quite as close this time.
Prediction: Falcons 24, Panthers 17
NFL power rankings Week 10:Eagles, Vikings, Bills, Chiefs lead NFL playoff picture
Sunday early football games
Seattle Seahawks vs. Tampa Bay Buccaneers, 7:30 a.m., NFL Network
The Buccaneers are favored in this game, but we really like how Geno Smith and the Seahawks are playing. Give us Seattle in an upset.
Prediction: Seahawks 27, Buccaneers 21
Minnesota Vikings vs. Buffalo Bills, 11 a.m., Fox
Will this be the game of the week? These teams have just three losses between them. We like the Bills to bounce back in a close one.
Prediction: Bills 24, Vikings 21
Detroit Lions vs. Chicago Bears, 11 a.m., Fox
Justin Fields has become must-see TV in recent weeks. We don't think the Lions will be able to contain him.
Prediction: Bears 30, Lions 20
Jacksonville Jaguars vs. Kansas City Chiefs, 11 a.m., CBS
The Chiefs needed overtime to beat the Titans in Week 9. We don't anticipate this game being nearly as close.
Prediction: Chiefs 35, Jaguars 17
NFL Week 10 picks, predictions:
- Falcons vs. Panthers | Seahawks vs. Bucs | Vikings vs. Bills
- Lions vs. Bears | Jaguars vs. Chiefs | Browns vs. Dolphins
- Texans vs. Giants | Saints vs. Steelers | Broncos vs. Titans
- Colts vs. Raiders | Cowboys vs. Packers | Cardinals vs. Rams
- Chargers vs. 49ers | Commanders vs. Eagles | For subscribers
Cleveland Browns vs. Miami Dolphins, 11 a.m., CBS
We really like the way Tua Tagovailoa is playing right now. This game could see a lot of points.
Prediction: Dolphins 35, Browns 31
Houston Texans vs. New York Giants, 11 a.m., CBS
It hasn't been pretty, but the Giants are having a special season. It isn't over yet, either.
Prediction: Giants 20, Texans 13
New Orleans Saints vs. Pittsburgh Steelers, 11 a.m., Fox
We don't have confidence In either of these teams, but we have more confidence in the Saints.
Prediction: Saints 21, Steelers 13
Denver Broncos vs. Tennessee Titans, 11 a.m., CBS
We like the Titans' chances to bounce back at home, with or without Ryan Tannehill at quarterback.
Prediction: Titans 28, Broncos 24
How to watch:NFL Week 10 schedule, television information
Sunday late football games
Indianapolis Colts vs. Las Vegas Raiders, 2:05 p.m., CBS
Frankly, we're shocked both of these teams are this bad. The home team should be able to bounce back here, barely.
Prediction: Raiders 24, Colts 23
Dallas Cowboys vs. Green Bay Packers, 2:25 p.m., Fox
The Packers have to win sometime, right? It just isn't going to be in Week 10 against a rested Cowboys team.
Prediction: Cowboys 31, Packers 21
Arizona Cardinals vs. Los Angeles Rams, 2:25 p.m., Fox
Both of these teams should be far better than they are right now. At least the Rams and their fans have a Super Bowl title to fall back on.
Prediction: Rams 27, Cardinals 17
Super Bowl odds:NFL Week 10 betting odds for every NFL team to win 2023 Super Bowl
Sunday Night Football schedule
Los Angeles Chargers vs. San Francisco 49ers, 6:20 p.m., NBC
Injuries have decimated the Chargers' offense. It will show against the 49ers' defense.
Prediction: 49ers 30, Chargers 20
Monday Night Football schedule
Washington Commanders vs. Philadelphia Eagles, 6:15 p.m., ESPN
How long can the Eagles keep the magic going? They shouldn't have any problem moving to 9-0 this week.
Prediction: Eagles 38, Commanders 21
NFL Week 10 odds:Point spreads, moneylines, over/unders, totals for Week 10 NFL games
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on Twitter @Jeremy_Cluff.